Protein helped and exercise helped me. Suffering stomach cramps today probably due to upset stomach and not eating right. Avoid things that may worsen the symptoms, such as heavy or greasy/fatty, spicy or acidic foods (lemons, tomatoes, oranges). I do have to rest far more than I used to, although I manage to cope with a busy full time job. The infusion will be slowed or stopped if this occurs. Include fiber in your diet (fruits and vegetables), drink 8-10 glasses of non-alcoholic fluids a day, and keep active. That was on the dose dense A/C. 4 days after having it I was so sick I could not go to work. Plan times to rest during the day and conserve energy for more important activities. Differences in clearance for the two PRINT particles suggest that shape plays a role in reducing clearance by the MPS and enhancing tumor delivery. You should feel a lot better in about a week's time. That finished months ago, but she's still whacked by the docetaxel on and off. Hi. APAP vs. CPAP: Whats the Best Machine for Sleep Apnea? To view profiles and participate in discussions please. MYTH #6: I'll permanently lose all my hair after chemo. Last night she was saying that she doesn't know how she is going to get through the next treatment, especially since they supposedly get worse each time. A post shared by Soulcake (@soulcake) on Jul 18, 2017 at 9:40pm PDT. Worst effect in Cycle 2 and 3 was in lack of taste and the awful chemical tast in my mouth at all times. . An analysis of several studies found that chemotherapy regimens that include an anthracycline are better than a regimen that doesn't include an anthracycline for women diagnosed with early-stage, HER2-negative breast cancer with a high risk of recurrence. I have been told that they have FL First Lady wants to explore new strategies for Cancer Tre ILC: Double Mastectomy-all breast tissue removed - Pathology showed positive margins. Alternative therapies can help for relaxation althrough at th emoment i go for the glass of wine cure. I had been doing the paracetamol and ibuprofen as previously advised but the Oncology Sister told me that ibuprofen is not suitable for chemo patients as they can interfere with treatment and other medications, since switching I have had more relief and felt better. My poor hubby had to give them me.but they hurt and make me have achy legs.plus with the chemo sleepless nights. Chemotherapy drugs can deplete your supply of red blood cells, the cells that carry oxygen throughout your body. And yes, for me at least, it is cumulative and is a bit worse each cycle. It will help clear it and make eating slightly more tolerable. Avoid smoking and chewing tobacco, drinking alcoholic beverages, and citrus juices. Common side effects of Tax are bone aches and pains, sore mouth/mouth ulcers, oral thrush, loss of taste. Found the freeze gell hit the joint areas better and gave relief. nausea and vomiting. I am trying to keep focused and positive to get through this. Drink 8-10 glasses of non-alcoholic, un-caffeinated fluid a day to prevent dehydration. Thank you for taking the time to send me such an inspirational account of your experience, reading it almost made me cry but it hit in all the right places to make me fight this and get on with the treatment. They have said I don't need to have a scan which I have found strange as I need the reassurance that all is okay and it hasn't gone anywhere else. The recent positive findings seen with docetaxel come from 2 randomized trials: CHAARTED and STAMPEDE. Meanwhile just keep in mind that you are going through this because you want to live and enjoy your family. Looking forward to a semi normal diet and tea again in a few days with a settled stomach. Avoid large crowds and people who are sick (i.e. Some chemotherapy medications can cause neuropathy (numbness or tingling in your hands and feet). And it may even boost our immune systems. Anyway, like you im a very positive person, was dealing very well with it all, had 3 rounds of EC first.. Now two rounds left of Docetaxal.. Im floored.. I have a soup maker so maybe I should give it a go. By the second cycle,my nausea would start as Im getting my infusion. OR. I did start taking codeine and paracetamol but that caused severe constipation and bowel issues. The interval between each treatment gives your body time to recover. The Docetaxel/Taxotere is the drug causing this nasty side effect. Weekly taxol : which days will be worst. In 2022 . Had tummy issues mostly diarrhoea but managed to get a good stopper tablet. I went back to work on Tuesday, but wasn't feeling the greatest. Of course, we each respond as individuals. Thank you, hope you continue to be well. X, Hi sorry to hear it is so terrible for you they may need to up your anti nausea meds this happened to me at the start but once the added in onother anti nausea drug it was much better talk to your nurse there must be something to improve your side effects, Thinking of you hugs and best wishes you can do this , Thanks Mags for your message. The recommended dose of TAXOTERE is 60-100 mg/m2 administered intravenously over 1 hour every 3 weeks. I often feel like it's too much and want to give in. I have at times reached my lowest and questioned if I can continue to put my body through this poison. I ended up in hospital 4 days after treatment.. Keep your fingernails and toenails clean and dry. X. Hi everyone, I start taxatere in feb.can anyone please tell me If I have to have the horrid injections for bone marrow while having that chemo? Laughter is fast-acting, too. This medication can cause severe side effects if given to a patient whose liver function is abnormal. Stay well hydrated. Days 1 & 7, I was tired but could function to some degree - I made it to infusions. I got that too. Keep reading to learn more about what to expect on your worst days on Taxotere. Re: Docetaxel help please!! Taxotere injections can cause serious and life-threatening fluid retention(edema). 1. Signs of a reaction can include: feeling hot or flushed shivering itching a skin rash feeling dizzy a headache feeling breathless or wheezy swelling of your face or mouth pain in your back, tummy or chest. But by the sound of it a lot of you needed that third week to recover, she won't have that. Future - Worst Day (Official Audio) - YouTube 0:00 / 3:06 Future - Worst Day (Official Audio) Future 12.5M subscribers Subscribe 2.5M views 1 year ago #Future #WorstDay Future - Worst. So my advice is dont be scared to ring the chemo hotline, they know what to advise and whether or not you should go in.. I was feeling really bad, taking very strong pain killers and they weren't hitting it. Try saltines, or ginger ale to lessen symptoms. I have anti nausea meds that work its just the new chemo is a lot stronger. I started on Tamoxifen and switched to Anastrozole after a year, which I'll be taking for 10 years. . Common reported side effects of Taxotere (docetaxel) include: Injection site pain or swelling Temporary hair loss Nausea Vomiting Diarrhea Constipation Loss of appetite Fingernail or toenail changes Doctors may lower the dose or prescribe drugs that reduce the risk of allergic reactions to deal with these types of side effects. With NiceRx you'll always pay a flat monthly fee of $49. I would go to work when I was able to and just did what I could. I have just had 4 cycles of FEC and other than the 3rd one, coped OK and carried on working a combination of at home and in work on my good week. If this were to happen, the only fix is an invasive surgery. Docetaxel interferes with the function of microtubules, resulting in inactive microtubule bundles, causing cells to die. Patients may struggle with never-ending itchiness, swollen eyelids, and an increase in "floaters." I actually postponed Rads for a few weeks so that we could go away. Xx, Thanks Berylynn. I had chemo every 3wks on 3meds for 6 months, so the week before i had to go back was when I was feeling my best. Taxotere is a chemotherapy drug made by Sanofi-Aventis. And that's it! with 5 mg prednisone twice a day continuously (2.3) GC: 75 mg/m 2followed by cisplatin 75 (both on day 1 only) fol lowed by fluorouraci 750 mg/m2 per day as a 24 -hr . Other effects for me are tingling in feet, skin peeling off, mostly in feet, toe nails highly sensitive. I was diagnosed with grade 3 breast cancer in may. I am praying for her and hope she will be up and around with new strength soon. Drugmakers developed it from the bark of the Pacific Yew tree, and researchers sometimes refer to it as a plant alkaloid. But by my third week I felt somewhat normal, would tire quick but normal. As long as I moved and tried to do those things, even though I felt crappy, I would always feel better afterwards. Best wishes to everyone on this treatment and you will come out the other side. Hope you are well now too. And a bit of movement / chatting / getting out of the house helps.. If the area of injection becomes red, swollen, or painful at any time during or after the injection, notify your care team immediately. If you experience nausea, lack of appetite, or other eating problems, discuss solutions with your doctor or nurse navigator. I had my 2nd cycle of Docetaxel yesterday. Hair generally starts to regrow soon after treatment is completed. Bacon, ham, and onion can add flavor to vegetables. For cycle 2 I used a great mouthwash - Difflam and have had no sore mouth problems since. I followed all the advice and recommendations given by the medical team and tried to be positive about the treatment working to fight the cancer but it has been hard. Even if it is to moan. I was on taxotere, carboplatin, and Herceptin every 3 weeks. For prostate cancer, chemo drugs are typically used one at a time. I also lost all my taste buds. You won't be up to doing anything. Do not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Talk to your care team about these recommendations. fatigue. I am a small women (112 lbs. You have given me some great pointers and hopefully I can be calmer about my next 2 cycles. I have been doing research and have learned of some pretty serious side, i.e., mouth sores, possible stroke or heart attack, loss of hair, I think one person even said they'd lost a toe! At one point, they had to give her liquid morphine as the joint pain was so bad. Platelets help your blood clot, so when the count is low you are at a higher risk of bleeding. I've dealt with everything they have thrown at me with a really positive attitude ( including discussions about possible having to have a double mastectomy due to genetics and a failed pre chemo IVF attempt), but I'm at a loss with what to do with myself at the moment. Your story kinda reads similar to my wife's when she was on Docetaxel. Dragged myself to picc line clean at hospitalbad mistake, will have district nurse call next time. Will try the mouthwash as that is also a problem, I have a drink and seconds later my mouth is so dry again! Cancer treatment can affect your appetite and, in some cases, the side effects of treatment can make eating difficult. The effects of chemo are cumulative. Your doctor will prescribe the exact regimen. Cycle 1 was not too bad - aching legs and joints, lost toe and fingernails, numness in toes, soles of feet and fingertips, sore mouth (had to eat and drink through a straw) and nausea. Painkillers, she had all the same things as you. Cannot speak personally here other than as the wife of a hubby who had chemo at the end of 2012 and was equally 'lousy' with all the side effects. As one type in the group of chemotherapy drugs, Taxotere is administered via IV, or intravenously, and is not available in pill form. An absolute pleasure to have helped. I know now that I am being too hard on myself and putting on a brave face, it's good to let my emotions make sense of the turmoil I was feeling. So those were constant through the whole process. We started working from home the week after the infusion. 5 year old not there yet. Taxotere is one of many breast cancer chemotherapy drugs. Your oncology care team can recommend medications to relieve diarrhea. the feet problems still continues now and I have now lost all toenails and most fingernails - bu the important thing is that they looked great with fuschia Shellac for my wedding day and honeymoon! My concern is that with my weight, history of smoking and alcohol my body will not tolerate all of this. This chemo certainly throws everything at us to endure. * To protect your identity do not use your full name. Was 48mu for EC but took 7Tax was 30mu. Do not cut cuticles or ingrown nails. Chemotherapy kills regular cells, as well as cancer cells, and this is why side effects occur . At least week three is getting close, mine starts next Tuesday. Researchers spent YEARS finding chemotherapy compounds that could attack prostate cancer cells. He recommended that I halve the dose, but I'd had previous allergic . The care I have had from diagnosis to today has been quick, I begin Radiotherapy begining of March. She only took that a couple of times. I've just had my first Docetaxel 5 days ago and boy am I sufferingshooting painsin lower back, kidney area,legs andshoulders for two days now. You will have docetaxel as an outpatient. I was prescribed preventative FEC-T but because I was getting married and honeymooning in July, they decided to do the Taxotere first and cycle 3 was combined with my whole radiotherapy treatment. Been told its best to as it helps the operation be morebsuccessful. Can eat, not been sick, not taken antisickness meds, but nausia with ukky taste but poor sleep got worse. Let your oncology care team know if you have any excess bruising or bleeding, including nose bleeds, bleeding gums or blood in your urine or stool. Talk to your healthcare team for helpful tips on dealing with this side effect. I wish you the best with these meds. My wonderful wife took me away between chemo and Rads, it was a truly enjoyable break, 5 days in a cabin in the woods (provided free by The Willow Foundation). I have no effects, no CRASH, no anything ((. It took a few months for my taste to come back. TAXOTERE (docetaxel) injection, for intravenous use . I completed 4 doses of EC (1 every 3 weeks). You don't sound negative, you just sound disheartened that after following all advice you are still suffering and also that you are finding treatment difficult. Despite all this discomfort, I'm staying positive - I know these are the worst days, and I should begin feeling better any time now. I just had my first Docetaxal dose over a week ago.. Have you rang your chemo hotline? I spent a week in hospital after the 3rd Taxotere + radiotherapy. What Is the Taxotere Mechanism of Action? As all of us are!For ME - A/C was much easier than Taxol! (Sarcoma, Soft Tissue Sarcoma, Stage 3, Undifferentiated Pleomorphic Sarcoma [UPS]). Make sure that those around you understand that while the pain peaks, you need absolute rest. They can help you decide what will work best for you. Severe symptoms are less common but require dose modifications. Your fingernails/toenails may become dark, brittle or fall off. I had my first T part last Thursday and I to have struggled with severe tiredness but worst is the pains in my legs and arms. But I know that's just wrong. You may notice chills, a sore throat, achiness, and swollen glands and lymph nodes. some were bad and some were tolerable plus i also had insomnia because of the steriods.Tell Donna to hang in thereand good luck to you Bob! I was informed that I would need a mastectomy as to the way the tumour is growing in the breast. If red meat is a problem, eat chicken, turkey, eggs, dairy products, and fish without a strong smell. Shower or bathe daily and perform frequent. Can I just say thank you so much for the great advise, I am going through Taxotere part of chemo at the moment and it is just horrible, my poor hands are the worst, they are burning like mad but have been prescribed Piriton and paracetamol to try and rectify overnight and have to go to hospital in the morning that does seem to have helped. I was on taxotere and idI was on taxotere and id have my treatments on monday, and wednesday & thursdays were my bad days. I was so tired, and I wasnt expecting that level of fatigue. If docetaxel does not work or stops working, cabazitaxel (Jevtana) may . Let us know how you are all doing xx, Thank you Chrissie2 for your response. The ResMed machine is a medical device used to treat sleep apnea, a condition that causes pauses in breathing during Obstructive sleep apnea is a sleep condition in which a person's airway is obstructed during sleep, resulting in shallow breathing Dry eye is a common condition that can range from minor irritation to severe discomfort. So into hospital she went each time. After starting docetaxel, many men experience the improvements in disease-related symptoms, including pain, fatigue and loss of energy. I had the FEC-T chemo first, from December 2013 to April 2014. Taxotere is a mitotic inhibitor that interferes with your bodys cell division process. for use in the treatment of prostate cancer in the year 2004. One of the common types of chemotherapies for breast cancer, AC + T includes three drugs: doxorubicin (Adriamycin), cyclophosphamide (Cytoxan), and a taxane drug (Taxol, Taxotere . My doctor did reduce the docetaxen for me after the first one e and it made a difference, My advise is phone your doctor or key worker and ask if them if they can reduce the doseage. X, Reading all the comments, many of us have been through the mill with this 4th treatment. If you feel unwell or have any of these signs, tell them straight away. xx. Had a DIEP flap reconstruction in August 2016 and am currently waiting to get my date for another op to uplift and reduce my right boob to match the new one. While on cancer treatment, and for a period after, you may need to adjust your schedule to manage fatigue. I don't know about AC, but when I was on TC, I was told that it's not cumulative, so I would not be feeling worse as chemo progressed.Good luck to Donna, I hope she gets the rest she needs. i have been lucky to have good support but the weakness in my legs and arms and neck, have been bad and still are two weeks later I feel my body just wants to colapse when I get to the sink to try to do the dishes, so I have to sit down and wait until I feel better. None worked. July 16, 2018. I think I am coming to the end of feeling like I have hit by a bus with the chronic aches in all my joints and bones. The drug can cause tear duct closures which can cause permanent tearing. This combination of meds had the remarkable result of shrinking my very large tumor by a full 50 percent! In the larger STAMPEDE trial (2962 patients), adding docetaxel to standard hormonal therapy significantly improved survival among men with newly diagnosed, hormone-nave advanced prostate cancer. When thered cell count is low, you may feel tired or weak. Amelia L. (Breast Cancer, IDC, Stage 1, ER+, PR+, HER2-). Men initially treated with Taxotere had favorable outcomes compared to those who were initially treated with Novantrone: Median overall survival was 22 months for men treated with Taxotere first and 15 months for those treated with Novantrone first. Take regular Paracetamol and Ibruprofen all day every day. So always stay in touch with the team.. Im out now on antibiotics.. Health Advice: What Is A CPAP Machine And How Does It Work? I have been given so many tablets with this cycle which need to be taken with food but find eating almost impossible due to chemo mouth explosion of thrush despite being on medication. Dragged myself to picc line clean at hospital.bad mistake, will have district nurse call next time. All content 2023 Trustees of the University of Pennsylvania. - currently getting pumped of the lovely docetaxel! Best wishes Jules xxx. So would recommend this. I finished T & C on April 1 (total of 6 treatments). Sounds like you have had quite a week, similar to mine. Fatigue. Some of the chemo drugs used to treat prostate cancer include: Docetaxel (Taxotere) Cabazitaxel (Jevtana) Mitoxantrone (Novantrone) Estramustine (Emcyt) In most cases, the first chemo drug given is docetaxel, combined with the steroid drug prednisone. They had no idea, and still have no idea why her body was reacting the way it was. I completely avoided this by doing a few things (recommended by American and French oncologists, and also by many girls who have had the courage to try these things). In some ways was easier, in others was more taxing (pun intended)! Humor can also lessen anxiety and discomfort, allowing cancer patients to talk more openly about their concerns and fears. Have had one cycle of that and have the second next week. Repeat cycle every 3 week. Recurrence of endometrial cancer in lymph nodes. Give yourself a great big pat on the back, you are nearly there!!! If you are not eating enough, nutritional supplements may help. It, like other chemotherapy medications, can have severe side effects. You may wear nail polish, but not fake nails. It happens most often in the legs and feet, but it isnt unusual to see swelling in the hands, arms, and abdomen. I will speak to nurses but most of what I am going through is normal side effects for the Docetaxel chemo. for me it was the 4th and 5th daysi had my first AC on June 10 (a Thursday), and the worst days for me were Sunday and Monday. I only have one more left now as it was my 5th cycle of chemo regimen FEC x 3 then Docetaxel x 3 . Docetaxel is given by intravenous (IV, into a vein) infusion, usually over an hour. In some cases, you might feel extra hungry or gain weight. Leg pain also bad tonight, I am on day 5 after first Taxotere chemo so I suppose it's working at its height at the moment, hope it gets better in the coming days! This study found that women diagnosed with hormone-receptor-positive breast cancer did benefit from getting a taxane. I had cisplatin , taxotere and the neulastra shot and really hurt the 1st infusion but not the others after starting the clariton. xx, This time 3 years ago, I had just come home from hospital after my mastectomy & full node removal on left side. The most common chemotherapy drug for prostate cancer is docetaxel (Taxotere), which is usually given with prednisone, a steroid medicine. The ninth-largest drop was . So I feel that is a positive thought. Around that time I had violent throw up for a couple of sessions, and then that was it. Ps Voltarol Gel is good rubbed in for the lower back pain. Hi Dolbycat, were in this side by sideI missed out on the mouth thrush, came away with chemo ward mouthwash not used it much. It had to have been that I just did too much. Try to eat five or six small meals or snacks throughout the day, instead of 3 larger meals. Genoa M. (Breast Cancer, Invasive Ductal Carcinoma [IDC], Stage 3, HER2+). It is a horrid drug and going through the side effects of chemo is just unbearable at times (for me and some others unfortunately!). Some common Taxotere side effects include: Heres what cancer patients had to say about their experiences with Taxotere: I started chemotherapy. Then I will start on radiotherapy. And pineapple sounds a good idea too! Take pain killers when you need them. Grapefruit can change how your body absorbs this medication. I need to focus on this and get back on track. Avoid mouthwashes that contain alcohol. Though chemo is officially kicking my butt, I want you all to know that I am determined to maintain my upbeat attitude and sense of humor through it all, no matter . It was stage Three I though thats it,the end. It is very frustrating when you just want to get on with life but he was advised to 'listen to what his body was saying and act accordingly' on an hour to hour basis if necessary. Taxotere was my aggressive chemo, and it caused the majority of the side effects the hair loss, nausea, all these different things. Epiphora One of the most major Taxotere side effects is epiphora or, in simple terms, watery eyes. Everything tasted like cardboard, which sucked because I love to eat. As the saying goes, "Hindsight is 20/20 . In its mechanism of action, Taxotere prevents the inner structures of cancer cells from building, which stops cell division and eventually leads to cancer cell death. After this drug I could only eat about three things, dry crispbreads, toast and marmite and mandarin oranges - I lived almost exclusively on mandarins because everything else tasted disgusting. Yesterday I finally got these problems under control. I got off lightly on the 4 AC, only had a couple of very bad days each cycle. Good luck with your next cycle and hopefully you too will benefit from the treatment. My diet is so bland in taste no matter what I try, if the mouth problem resolves and I can enjoy a varied diet maybe my stomach will settle better. (And day 12 after my third and final Tax - I'd probably still say the same. Today is the first day of actually feeling better after first cycle of Docetaxel, I am going to enjoy this last week before the next cycle of chemo starts.
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